Electrochemical synthesis of metal oxide nanoparticles for preparation of creatinine sensor

Electrochemical enzymless sensors are attractive by researchers due to their advantages includinglow fabrication cost, good selectivity and high stability. Transition metal oxides are a suitablematerials for preparation of enzymless creatinine sensors due to their ability in interaction withcreatinine. The present paper is devoted to an electrochemical synthesis of iron oxide nanoparticlesfor preparation of an impedance-based enzymless creatinine sensors. The electrodeposition of ironoxide on the surface was carried out through a constant potential method. The morphology of theprepared surface was studied by Field emission scanning electron microscopy (FESEM).Electrochemical impedance spectroscopy (EIS) was used as impedimetric method fordetermination of creatinine in samples. The results of EIS indicated an increasing trend in value ofcharge transfer resistance (Rct) from ۱۲.۷ kΩ for ۶۰ μM creatinine to ۱۴.۴۵ kΩ for ۸۰ μMcreatinine. The prepared sensor can be used in rapid detection of creatinine in real samples.